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Basaloid squamous cell lung carcinoma
Basaloid squamous cell carcinoma (Bas-SqCC) is an uncommon histological variant of lung cancer composed of cells exhibiting cytological and tissue architectural features of both squamous cell lung carcinoma and basaloid carcinoma.
==Classification==
Lung cancer is a large and exceptionally heterogeneous family of malignancies. Over 50 different histological variants of lung cancer are explicitly recognized within the fourth (2004) revision of the World Health Organization Classification of Lung Tumours ("WHO-2004").〔 Many of these entities are quite rare, have only been recently described, and remain poorly understood.
Basaloid forms of lung carcinoma were first described in the peer-reviewed medical literature by Dr. Elisabeth Brambilla and her colleagues in 1992.
In the third revision of the World Health Organization lung tumor typing and classification scheme, published in 1999, basaloid variants of both squamous cell lung carcinoma (SqCC) and large cell lung carcinoma (LCLC) were recognized as distinct entities.〔 In the fourth revision (2004) of the WHO system (currently the world standard) Bas-SqCC is classified as one of four recognized variants of squamous cell lung carcinoma.〔 As a variant of SqCC, it is considered a non-small cell lung cancer (NSCLC).
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